Believers Church Medical College Hospital, Thiruvalla
The Advanced Flow Cytometry Laboratory (AFCL) at BCMCH delivers high-precision cellular immunophenotyping using state-of-the-art DxFLEX Clinical Flow Cytometry. AFCL supports rapid and accurate diagnosis, subclassification, and therapy guidance for hematologic malignancies, immune disorders, and plasma cell dyscrasias.
Flow cytometry enables real-time, multiparametric analysis of individual cells, forming a cornerstone in modern hematology and immunology. AFCL integrates expert hematopathology, automated analytical workflows, and stringent quality systems to ensure reliable, clinically meaningful results.
Why Flow Cytometry at BCMCH?
Flow cytometry plays a critical role in:
Core Medical Team
Dr. Bonnie Anna George, MBBS, MD
Consultant Hematopathologist
Specializes in diagnostic hematopathology, integrating flow cytometry with morphology, cytogenetics and molecular hematology for precise disease classification.
Dr. Abel Jaison, MBBS, MD
Assistant Professor, Department of Biochemistry
Focuses on cellular immunology and development of diagnostic algorithms that complement precision hematology services.
Mr. Harikrishnan Babu
Senior Research Scientist – Flow Cytometry
Expert in advanced multicolor flow cytometry applications, assay optimization and high-complexity immune profiling.
Diagnostic Services
AFCL provides a structured test menu built on international guidelines and clinical needs. All tests have a 24-hour TAT when received within sample cut-off times.
1. Comprehensive Acute Leukemia Immunophenotyping Panel
A full diagnostic panel for suspected acute leukemia.
Establishes lineage (AML, B-ALL, T-ALL), identifies blast populations, detects aberrant antigen expression, and supports WHO/ICC classification. Helps identify MPAL, ETP-ALL, APL-like AML and defines markers for MRD monitoring.
Recommended for:
BCMCH Proposed Rate: 10,600
TAT: 24 hours
2. Acute Leukemia – Basic Screening Panel
A frontline rapid panel used in emergency and triage settings to detect blasts and provide early myeloid vs lymphoid lineage orientation.
Recommended for:
BCMCH Proposed Rate: 7,450
TAT: 24 hours
3. Acute Leukemia – Secondary Immunophenotyping Panel
A problem-solving panel for cases with atypical, overlapping or ambiguous features. Assesses precursor markers, TCR subsets, cortical thymic markers, erythroid/megakaryocytic exclusion markers, and additional refinement parameters.
Useful for:
BCMCH Proposed Rate: 4,550
TAT: 24 hours
4. Lymphoid Screening Panel
A broad lymphoid evaluation panel used to triage suspected lymphoma, lymphocytosis, and abnormal lymphoid proliferations. Detects clonal B-cell populations, evaluates T- and NK-cell phenotypes, and identifies blast populations requiring leukemia panels.
Recommended for:
BCMCH Proposed Rate: 6,600
TAT: 24 hours
5. Lymphocyte Subset Analysis (TBNK Panel)
Provides quantitative assessment of T-, B-, and NK-cell subsets for immunodeficiency evaluations and therapy monitoring.
Recommended for:
BCMCH Proposed Rate: 3,850
TAT: 24 hours
6. Basic Myeloma Screening Panel
Assesses clonal plasma cells, differentiates neoplastic vs reactive plasmacytosis, and evaluates light-chain restriction.
Recommended for:
BCMCH Proposed Rate: 4,200
TAT: 24 hours
Sample Receiving & Turnaround Time
|
Day |
Sample Cut-off |
TAT |
|
Monday – Friday |
Till 12 PM |
24 hours |
|
Saturday |
Till 10 AM |
Before Monday 12 PM |
Sample Types:
Peripheral blood, bone marrow aspirate, body fluids (CSF, effusions), FNAC rinses, fresh lymph node tissue (not fixed).
Looking Ahead
AFCL is expanding its services to include:
Contact
0469-3503100 / 2703100
flowcytometry@bcmch.edu.in